Chart 3.

Absolute and relative contraindications to the use of oral anticoagulation

• Previous significant bleeding

• Previous intracranial bleeding

• Symptomatic bleeding in a critical organ (e.g., ocular, pericardial, medullary)

• High risk of bleeding

• Frailty/frequent falls

• Comorbidities (e.g., intestinal angiodysplasia, renal failure, blood dyscrasia)

• Lack of adherence to treatment

• Labile INR

• Anticoagulant intolerance

• Use of double antiplatelet therapy

• Refusal to use the medication

• Occupational risk

INR: international normalized ratio.