Table 2. SAR of Benzamide Core in the Presence of C-4 Fluoride.

^aAntiviral effect of compounds. After 65 h of treatment with compounds, the HepAD38 cells were harvested and intracellular HBV DNA was extracted and quantified (real-time PCR Assay).

^bCytotoxicity of compounds deteremined by cell viability assay using HepAD38 cells.