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. 2020 Jan 27;11(2):188–194. doi: 10.1021/acsmedchemlett.9b00578

Figure 4.

Figure 4

Crystal structure of NEP complexed with 13 (yellow). Zinc atom is shown in magenta. H-bonding interactions are shown as black dotted lines. Chlorine is colored green. (a and b) Two different orientations of the binding site are shown to provide clarity of the interactions. (c) Overlay of crystal structure of LBQ657 (cyan) on 13.