Table 2. Brain Uptake of Radioactivity after the Injection of Each ¹²⁵I-Labeled 6,5,6-Tricyclic Compound Derivative in Normal Mice^a and the Ratio of Their Radioactivity Accumulation (2 min/30 and 2 min/60 min).

	%ID/g in the brain			ratio
compd	2 min	30 min	60 min	2 min/30 min	2 min/60 min
[125I]10	3.11 ± 0.49	0.95 ± 0.11	0.40 ± 0.06	3.3	7.8
[125I]11	3.59 ± 0.32	0.27 ± 0.01	0.16 ± 0.01	13.2	22.4
[125I]12	3.69 ± 0.52	0.16 ± 0.03	0.09 ± 0.01	23.0	41.2
[125I]21	5.73 ± 0.21	0.21 ± 0.01	0.14 ± 0.02	27.6	41.6
[125I]22	5.66 ± 0.34	0.19 ± 0.04	0.10 ± 0.01	30.2	56.7
[125I]23	4.12 ± 0.68	0.20 ± 0.03	0.10 ± 0.01	20.5	41.8
[125I]BIP-NMe2b	3.98 ± 0.32	0.38 ± 0.03	0.16 ± 0.01	10.5	24.9

^aEach value represents the mean ± SD of five animals.

^bThe data were reported previously.