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. 2020 Feb 17;17:6. doi: 10.1186/s12987-020-0167-0

Table 2.

Transcranial magnetic stimulation (TMS) responses measured in this study

Definition Neuronal background Interpretation References
Motor threshold Glutamatergic system High motor threshold means decreased corticospinal excitability [33, 41, 42]
 Resting motor threshold (RMT) Corticospinal excitability (% of maximum stimulator output)
 Electric field (EF) Corticospinal excitability (induced electric field, V/m, at the cortex)
Silent period (SP) Corticospinal inhibition GABAergic system Long silent period means increased corticospinal inhibition [33, 38, 43]
Input–output curve (IO-slope) Dose-dependent response to TMS Synaptic connectivity and plasticity The steepness of the IO-slope reflects the level of synaptic connectivity and plasticity [40, 4446]

GABA gamma-aminobutyric acid