Table 2.
Definition | Neuronal background | Interpretation | References | |
---|---|---|---|---|
Motor threshold | – | Glutamatergic system | High motor threshold means decreased corticospinal excitability | [33, 41, 42] |
Resting motor threshold (RMT) | Corticospinal excitability (% of maximum stimulator output) | – | – | – |
Electric field (EF) | Corticospinal excitability (induced electric field, V/m, at the cortex) | – | – | – |
Silent period (SP) | Corticospinal inhibition | GABAergic system | Long silent period means increased corticospinal inhibition | [33, 38, 43] |
Input–output curve (IO-slope) | Dose-dependent response to TMS | Synaptic connectivity and plasticity | The steepness of the IO-slope reflects the level of synaptic connectivity and plasticity | [40, 44–46] |
GABA gamma-aminobutyric acid