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. 2020 Feb 7;10:87. doi: 10.3389/fonc.2020.00087

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Copyright © 2020 Li, Chen, Wei, Liu, Tian, Zhang, Zhu, Chen, Liu, Wang, Lin, Wang, Cai and Lv.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagram of AS events (A) and involved genes (B) that were significantly correlated with OS and recurrence. (C) Distribution of AS events of seven types. (D) Distribution of OS-associated AS events of seven types. (E) Distribution of recurrence-associated AS events of seven types. The UpSet intersection diagram shows seven types of OS (F)—and recurrence (G)—associated AS events in HNSCC. One gene may have up to four types of alternative splicing associated with patient survival or recurrence.