Table 3.
“Consensus” proteins shared between the 3 Mtb dormancy models found in the first 200 most abundant.
| Gene number | Product |
|---|---|
| Rv1908c | Catalase-peroxidase-peroxynitritase T KatG |
| Rv1837c | Malate synthase G GlcB |
| Rv1133c | Probable 5-methyltetrahydropteroyltriglutamate–homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) |
| Rv0685 | Probable iron-regulated elongation factor TU Tuf (EF-TU) |
| Rv1449c | Transketolase Tkt (TK) |
| Rv0440 | 60 kDa chaperonin 2 GroEL2 |
| Rv2744c | Conserved 35 kDa alanine rich protein |
| Rv0350 | Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa protein) (HSP70) |
| Rv2220 | Glutamine synthetase GlnA1 (glutamine synthase) (GS-I) |
| Rv3248c | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) |
| Rv3418c | 10 kDa chaperonin GroES (protein CPN10) (protein GroES) (BCG-a heat shock protein) (10 kDa antigen) |
| Rv3285 | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase (alpha chain) AccA3: biotin carboxylase + biotin carboxyl carrier protein (BCCP) |
| Rv3417c | 60 kDa chaperonin 1 GroEL1 (protein CPN60-1) (GroEL protein 1) |
| Rv0211 | Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA |
| Rv0951 | Probable succinyl-CoA synthetase (beta chain) SucC (SCS-beta) |
| Rv0896 | Probable citrate synthase I GltA2 |
| Rv1074c | Probable beta-ketoacyl CoA thiolase FadA3 |
| Rv0363c | Probable fructose-bisphosphate aldolase Fba |
| Rv1617 | Probable pyruvate kinase PykA |
| Rv1017c | Probable ribose-phosphate pyrophosphokinase PrsA (phosphoribosyl pyrophosphate synthetase) |
| Rv1310 | Probable ATP synthase beta chain AtpD |
| Rv2280 | Probable dehydrogenase |
| Rv2145c | Diviva family protein Wag31 |
| Rv3028c | Probable electron transfer flavoprotein (alpha-subunit) FixB (alpha-ETF) (electron transfer flavoprotein large subunit) (ETFLS) |
| Rv1886c | Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular alpha-antigen) |
| Rv1094 | Possible acyl-[acyl-carrier protein] desaturase DesA2 (acyl-[ACP] desaturase) (stearoyl-ACP desaturase) |
| Rv1023 | Probable enolase Eno |
| Rv1475c | Probable iron-regulated aconitate hydratase Acn (citrate hydro-lyase) (aconitase) |
| Rv0815c | Probable thiosulfate sulfurtransferase CysA2 |
| Rv3246c | Two component sensory transduction transcriptional regulatory protein MtrA |
| Rv1436 | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) |
| Rv3224 | Possible iron-regulated short-chain dehydrogenase/reductase |
| Rv2996c | Probable D-3-phosphoglycerate dehydrogenase SerA1 (PGDH) |
| Rv0860 | Probable fatty oxidation protein FadB |
| Rv3841 | Bacterioferritin BfrB |
| Rv0831c | Conserved protein |
| Rv0242c | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG4 |
| Rv2971 | Probable oxidoreductase |
| Rv3280 | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) |
| Rv3457c | Probable DNA-directed RNA polymerase (alpha chain) RpoA |
| Rv1308 | Probable ATP synthase alpha chain AtpA |
| Rv3846 | Superoxide dismutase [FE] SodA |
| Rv3274c | Probable acyl-CoA dehydrogenase FadE25 |
| Rv1630 | 30S ribosomal protein S1 RpsA |
| Rv2780 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) |
| Rv3914 | Thioredoxin TrxC (TRX) (MPT46) |
| Rv0667 | DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) |
| Rv2140c | Conserved protein TB18.6 |
| Rv0468 | 3-hydroxybutyryl-CoA dehydrogenase FadB2 |
| Rv3596c | Probable ATP-dependent protease ATP-binding subunit ClpC1 |
| Rv2334 | Cysteine synthase a CysK1 |
| Rv0462 | Dihydrolipoamide dehydrogenase LpdC |
| Rv0684 | Probable elongation factor G FusA1 (EF-G) |
| Rv0632c | Probable enoyl-CoA hydratase EchA3 |
| Rv2031c | Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3) |
| Rv2889c | Probable elongation factor Tsf (EF-ts) |
| Rv2215 | DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase |
| Rv2299c | Probable chaperone protein HtpG (heat shock protein) |