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. 2020 Feb 5;11:52. doi: 10.3389/fmicb.2020.00052

Table 3.

List of detected ARGs in isolates.

Gene Drug class Drug on panel Number of E. Number of E. Validation (%)
faecium isolates faecalis isolates
aac(6)-aph(2) Aminoglycoside GEN, KAN 3 (4) 39 (41) 93.4
aph(2)-Id Aminoglycoside GEN, KAN 8 (8) 0 (0) 100
aph(3)-III Aminoglycoside KAN 13 (13) 38 (42) 92.7
aadD Aminoglycoside KAN 1 (1) 0 (0) 100
erm(A) Macrolide ERY TYL 3 (3) 0 (0) 100
erm(B) Macrolide ERY TYL 27 (27) 54 (55) 98.8
cat Phenicol CHL 0 (0) 17 (18) 94.5
cat(pC221) Phenicol CHL 0 (0) 4 (4) 100
cat(pC194) Phenicol CHL 2 (2) 0 (0) 100
vat(E) Streptogramin QDA 20 (20) 1 (1) 100
vat(D) Streptogramin QDA 2 (2) 0 (0) 100
lsa(A) Streptogramin QDA 0 (0) 96 (97) 99
tet(L) Tetracycline TET 50 (50) 53 (53) 100
tet(M) Tetracycline TET 59 (59) 69 (70) 99.2
tet(O) Tetracycline TET 1 (1) 1 (1) 100
tet(S) Tetracycline TET 3 (3) 1 (1) 100
gyrA (S84F) Fluoroquinolone CIP 0 (0) 1 (1) 100
pbp5 (E630V) β-lactam PEN 3 (3) 0 (0) 100
pbp5 (ins D467) β-lactam PEN 1 (1) 0 (0) 100
pbp5 (ins S467) β-lactam PEN 3 (3) 0 (0) 100
spc Aminoglycoside None 3 (3) 0 (0) 100
lnu(A) Lincosamide None 0 (0) 2 (2) 100
lnu(B) Lincosamide None 38 (38) 15 (15) 100
mph(B) Macrolide None 1 (1) 0 (0) 100
msr(C) Macrolide None 85 (85) 0 (0) 100
dfrD Trimethoprim None 0 (0) 1 (1) 100
dfrG Trimethoprim None 0 (0) 7 (7) 100
Total 325 (327) 400 (409) 99.15

The numbers represent their prevalence within the analyzed dataset, that was established by sraX. In parentheses are shown the original values reported by Tyson et al. (2018b). For computing the confirmation rate, only those ARGs and SNPs which were coincidental in both studies were considered.

Bold character indicates the corroborated global average validation rate.