Summary of findings 3. Treatment of UI after radical: combinations of treatments versus no treatment for postprostatectomy urinary incontinence.
| Treatment of UI after radical: combinations of treatments versus no treatment for postprostatectomy UI | ||||||
| Patient or population: patients with postprostatectomy UI Intervention: Treatment of UI after radical: combinations of treatments versus no treatment | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Control | Treatment of UI after radical: combinations of treatments versus no treatment | |||||
| Number of incontinent men with 3 to 6 months | 53 per 1000 | 150 per 1000 (17 to 1000) | RR 2.85 (0.32 to 25.07) | 39 (1 study) | ⊕⊝⊝⊝ very low1,2,3,4 | |
| Urinary Incontinence Quality of Life Score (ICIQ‐SF) after 12 months | Study population | Not estimable | 0 (0) | See comment | ||
| See comment | See comment | |||||
| Moderate | ||||||
| Adverse events ‐ PFMT + anal EStim + BFB | 0 per 1000 | 0 per 1000 (0 to 0) | RR 4.86 (0.24 to 99.39) | 138 (1 study) | ⊕⊕⊝⊝ low2,4,5 | |
| Economic Analysis using QALY ‐ not reported | See comment | See comment | Not estimable | ‐ | See comment | |
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio | ||||||
| GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. | ||||||
1 Random sequence generation and allocation concealment unclear 2 Not applicable, only one trial 3 No explanation was provided 4 Funnel plot cannot be used as there is only one trial 5 95% CI is very wide (0.24 to 99.39)