Table 3.
Characteristics of Patients with Diabetic Foot Disease with or Without Sarcopenia
| Non-Sarcopenia | Sarcopenia | P value | |
|---|---|---|---|
| Gender (male/female) | 85/81 | 70/21 | <0.001 |
| Age (year) | 64.90±10.62 | 68.74±11.39 | 0.006 |
| Duration of Diabetes (year) | 10(5,18) | 9(4,15) | 0.215 |
| Duration of DFD (year) | 1.0(0.3,3.0) | 2.0(0.7,4.0) | 0.044 |
| BMI (Kg/m2) | 24.87±2.85 | 21.51±2.30 | <0.001 |
| History of foot ulcer (%) | 27.1 | 23.5 | 0.522 |
| Smoking (%) | 43.9 | 65.7 | 0.001 |
| Hypertension (%) | 59.4 | 57.8 | 0.810 |
| Coronary heart disease (%) | 15.5 | 29.4 | 0.007 |
| Cerebrovascular disease (%) | 9.7 | 12.7 | 0.440 |
| White Blood Cell (*109/L) | 8.22±3.62 | 9.12±4.19 | 0.113 |
| Hemoglobin (g/L) | 119.03±18.89 | 115.73±23.24 | 0.214 |
| Neutrophil (*109/L) | 71.83±9.49 | 73.37±10.45 | 0.224 |
| ALT (U/L) | 21.11±14.68 | 18.72±15.61 | 0.102 |
| AST (U/L) | 17(13, 27) | 17(13, 23) | 0.427 |
| Creatinine (μmol/L) | 77(58, 97) | 81(66, 114) | 0.078 |
| Uric Acid (μmol/L) | 285.52±105.27 | 287.31±111.99 | 0.897 |
| UACR (mg/g) | 427.0(11.6, 225.5) | 124.7(507.1, 947.8) | 0.010 |
| Triglyceride (mmol/L) | 1.43±1.52 | 1.39±0.68 | 0.397 |
| Total Cholesterol (mmol/L) | 3.73±1.06 | 3.82±1.14 | 0.577 |
| HDL-cholesterol (mmol/L) | 1.03(0.84, 1.22) | 1.00(0.79, 1.17) | 0.235 |
| LDL-cholesterol (mmol/L) | 2.14(1.64, 2.75) | 2.09(1.82, 2.83) | 0.479 |
| HbA1c (%) | 9.1(7.4, 11.7) | 9.9(7.5, 12.0) | 0.200 |
| NSS (point) | 4.67±2.12 | 5.44±1.62 | 0.032 |
| NDS (point) | 8.30±2.51 | 8.10±2.19 | 0.647 |
| Right motor tibial NCV (m/s) | 38.47±4.70 | 38.62±6.78 | 0.908 |
| Left motor tibial NCV (m/s) | 38.88±5.22 | 37.29±3.36 | 0.152 |
| Right motor peroneal NCV (m/s) | 40.42±8.02 | 37.99±7.15 | 0.208 |
| Left motor peroneal NCV (m/s) | 41.32±5.81 | 38.14±6.11 | 0.033 |
| Chronic Diabetic Complications | |||
| Diabetic Peripheral Neuropathy (%) | 94.2 | 96.1 | 0.500 |
| Peripheral arterial disease (%) | 14.8 | 33.0 | 0.001 |
| Diabetic Retinopathy (%) | 47.1 | 42.3 | 0.458 |
| Diabetic Kidney Disease (%) | 48.4 | 55.0 | 0.302 |
Notes: Data are presented as mean ± SD, median (interquartile range), or %.
Abbreviations: DFD, diabetic foot disease; BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; UACR, urinary albumin-to-creatinine ratio; HDL-cholesterol, high-density lipoprotein cholesterol; LDL-cholesterol, low-density lipoprotein cholesterol; HbA1c, glycosylated hemoglobin; NSS, Neuropathy symptom score; NDS, Neuropathy disability score; NCV, nerve conduction velocity.