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. 2020 Feb 14;8:e8378. doi: 10.7717/peerj.8378

Table 2. Univariable Cox (proportional hazard) regression analysis for the prognostic factors for stroke recurrence among first-ever stroke patients.

Models showing regression coefficients (b), crude hazard ratios (HR) with 95% confidence intervals (CI), Wald test and the corresponding p-values. The outcome variable was a time-to-event variable; where the event was stroke recurrence (present or absent) and the time was the number of years to develop the event (n = 8,576).

Variables Category/unit b Crude HR (95% CI) Wald test p-value
Age years −0.013 0.99 (0.98, 0.99) 11.00 <0.001*
HbA1c % 0.012 1.01 (0.93, 1.10) 0.07 0.790
Glucose in ED mmol/L 0.023 1.02 (1.00, 1.05) 3.20 0.075*
Random glucose mmol/L 0.0003 1.00 (0.95, 1.05) 0 0.990
Fasting glucose mmol/L 0.037 1.04 (1.01, 1.07) 5.80 0.016*
Body mass index kg/m2 −0.030 0.97 (0.88, 1.08) 0.32 0.570
Sex Female 0 1 0.10 0.750
Male 0.032 1.03 (0.85, 1.26)
Ethnic Malay 0 1 16.00 <0.001*
Non-Malay 0.659 1.93 (1.40, 2.67)
Hypertension No 0 1 9.80 0.002*
Yes 0.371 1.45 (1.15, 1.83)
Diabetes Mellitus No 0 1 12.00 <0.001*
Yes 0.350 1.42 (1.17, 1.73)
Dyslipidemia No 0 1 24.00 <0.001*
Yes 0.510 1.66 (1.35, 2.05)
Abnormal glucose level No 0 1 11.00 0.001*
Yes 0.377 1.46 (1.16, 1.83)
Abnormal triglyceride No 0 1 8.10 0.004*
Yes 0.374 1.45 (1.12, 1.88)
Abnormal TC No 0 1 2.80 0.096*
Yes 0.234 1.26 (0.96, 1.67)
Abnormal HDL No 0 1 0.10 0.750
Yes −0.043 0.96 (0.73, 1.25)
Abnormal LDL No 0 1 0.37 0.540
Yes 0.174 1.19 (0.68, 2.08)

Notes.

HR, Hazard ratio = exp (β); 95% CI exp(β-1.965*SE(β)), exp(β+1.965*SE(β)).

*

level of significance, p = 0.25.

Abbreviations

HbA1c
Glycosylated hemoglobin
ED
Emergency department
TC
Total cholesterol
HDL
High-density lipoprotein (cholesterol)
LDL
Low-density lipoprotein (cholesterol)