Table 2. Univariable Cox (proportional hazard) regression analysis for the prognostic factors for stroke recurrence among first-ever stroke patients.
Models showing regression coefficients (b), crude hazard ratios (HR) with 95% confidence intervals (CI), Wald test and the corresponding p-values. The outcome variable was a time-to-event variable; where the event was stroke recurrence (present or absent) and the time was the number of years to develop the event (n = 8,576).
Variables | Category/unit | b | Crude HR (95% CI) | Wald test | p-value |
---|---|---|---|---|---|
Age | years | −0.013 | 0.99 (0.98, 0.99) | 11.00 | <0.001* |
HbA1c | % | 0.012 | 1.01 (0.93, 1.10) | 0.07 | 0.790 |
Glucose in ED | mmol/L | 0.023 | 1.02 (1.00, 1.05) | 3.20 | 0.075* |
Random glucose | mmol/L | 0.0003 | 1.00 (0.95, 1.05) | 0 | 0.990 |
Fasting glucose | mmol/L | 0.037 | 1.04 (1.01, 1.07) | 5.80 | 0.016* |
Body mass index | kg/m2 | −0.030 | 0.97 (0.88, 1.08) | 0.32 | 0.570 |
Sex | Female | 0 | 1 | 0.10 | 0.750 |
Male | 0.032 | 1.03 (0.85, 1.26) | |||
Ethnic | Malay | 0 | 1 | 16.00 | <0.001* |
Non-Malay | 0.659 | 1.93 (1.40, 2.67) | |||
Hypertension | No | 0 | 1 | 9.80 | 0.002* |
Yes | 0.371 | 1.45 (1.15, 1.83) | |||
Diabetes Mellitus | No | 0 | 1 | 12.00 | <0.001* |
Yes | 0.350 | 1.42 (1.17, 1.73) | |||
Dyslipidemia | No | 0 | 1 | 24.00 | <0.001* |
Yes | 0.510 | 1.66 (1.35, 2.05) | |||
Abnormal glucose level | No | 0 | 1 | 11.00 | 0.001* |
Yes | 0.377 | 1.46 (1.16, 1.83) | |||
Abnormal triglyceride | No | 0 | 1 | 8.10 | 0.004* |
Yes | 0.374 | 1.45 (1.12, 1.88) | |||
Abnormal TC | No | 0 | 1 | 2.80 | 0.096* |
Yes | 0.234 | 1.26 (0.96, 1.67) | |||
Abnormal HDL | No | 0 | 1 | 0.10 | 0.750 |
Yes | −0.043 | 0.96 (0.73, 1.25) | |||
Abnormal LDL | No | 0 | 1 | 0.37 | 0.540 |
Yes | 0.174 | 1.19 (0.68, 2.08) |
Notes.
HR, Hazard ratio = exp (β); 95% CI exp(β-1.965*SE(β)), exp(β+1.965*SE(β)).
level of significance, p = 0.25.
Abbreviations
- HbA1c
- Glycosylated hemoglobin
- ED
- Emergency department
- TC
- Total cholesterol
- HDL
- High-density lipoprotein (cholesterol)
- LDL
- Low-density lipoprotein (cholesterol)