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. 2008 Jan 23;2008(1):CD001765. doi: 10.1002/14651858.CD001765.pub3

Kasper 1999.

Methods Design: RCT parallel group, 
 Blindness: double 
 Duration of study: 
 12 wks
Participants Single or multicentre: 
 Multicentre 
 Diagnostic criteria: DSM IV 
 Co‐morbidity allowed: 
 Secondary depression mild 
 Setting: 
 not described 
 Age: 
 18‐65 years 
 Other characteristics: 
 Men and women
Interventions No. of arms: four (citalopram 20mg vs 40mg vs 60mg vs placebo)
Outcomes Primary: 
 Change in YBOCS total score
Proportion of responders (defined as 25% reduction in YBOCS)
Notes 12
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear