Grahm 1989.
| Methods | Patients were randomised based on their date of admission. Patients admitted on odd days were entered into the control group and those admitted on even days into the experimental group. | |
| Participants | 32 patients with severe head injury and a GCS of 10 or less persisting for 6 hours. | |
| Interventions | 1) Early jejunal EN (under fluoroscopic, within 36 hr) n=17 2) EN (gastric feedings initiated after day 3 or when gastric function returned) n=15 | |
| Outcomes | Deaths LHS Infection Nitrogen balance | |
| Notes | Follow‐up until discharge. No loss to follow‐up. Four patients who should have been in the experimental group were placed in the control group because they were unable to start early feeding. To balance the size of the group four patients who should have been put in the control group were put into the experimental group. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | High risk | C ‐ Inadequate |