Beretta.

Methods	Multicentre randomised controlled trial. Generation of allocation schedule unclear. Part of a larger study of all gastrointestinal cancers (n=163). Analysis stratified by primary tumour site
Participants	88 patients with advanced metastatic colorectal cancer. All patients were 70 years or older.
Interventions	5‐Fluorouracil (500mg/m2 iv infusion) with racemic folinic acid (300mg/m2 iv bolus). Given weekly for 6 months or until progression vs Standard treatment (no further details provided)
Outcomes	Tumour response Overall survival Toxicity
Notes	Only published as an abstract. Cannot tell whether analysis was by intention to treat.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear