Bechelli 1985.
Methods | Allocation: randomised, stratified by schizophrenia subgroups. Blindness: double. Duration: 6months (preceeded by 7 day washout). | |
Participants | Diagnosis: schizophrenia (RDC). History: >2 episodes, stabilized for 3 months, duration ill ‐ mean 12 years (SD 9 years), informed consent. N=41. Age: range 19‐50 years, mean range 30‐33. Sex: all male. Setting: out‐patient clinic. | |
Interventions | 1. Pipothiazine palmitate: dose mean 75mg/IM/month**, range 50‐125 mg/injection. N=20. 2. Haloperidol decanoate: dose mean 100mg/IM/month, range 50‐100 mg/injection. N=21. | |
Outcomes | Mental state: BPRS.
Leaving the study early.
Additional medication.
Adverse effects: AIMS, Bordeleau Scale. Unable to use ‐ Global impression: CGI (no data). Weight measures: non‐clinical outcomes (data not usable). |
|
Notes | * Spitzer 1997 ** Mean dose of PP reported as 75 mg in the abstract and 65mg in paper. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |