Dencker 1973.
Methods | Allocations: randomised. Blindness: double. Duration: 1 year (3 phases: adjustment ‐ 3 months, 1st maintenance ‐ 3 months, 2nd maintenance ‐ 6 months). | |
Participants | Diagnosis: schizophrenia. History: duration ill >5years. N=67. Age: mean 41 years, range 18‐65. Sex: 51M, 14F. Setting: community & hospital. | |
Interventions | 1. Pipothiazine palmitate: dose mean 50 mg/IM/month, range 25‐400 mg/IM. N=31. 2. Fluphenazine decanoate: dose mean 6.25 mg/IM/month, range 3.1‐50 mg/IM. N=34. | |
Outcomes | Global rating.
Leaving the study early.
Additional medication.
Adverse effects: EPS, TESE.
Depression: HRSD. Unable to use ‐ Mental state: BPRS (no SD). Cognitive function: handwriting test (no usable data). Work capacity: ADL, SRE (no usable data). |
|
Notes | Authors contacted. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |