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. 2004 Jul 19;2004(3):CD001720. doi: 10.1002/14651858.CD001720.pub2

Simon 1978.

Methods Allocation: randomised. 
 Blindness: open. 
 Duration: 18 months.
Participants Diagnosis: schizophrenia (French classification system). 
 History: duration ill <3years, range 3‐10 years. 
 N=181. 
 Age: 21‐45 years. 
 Sex: 117M, 64F. 
 Setting: community/hospital.
Interventions 1. Pipothiazine palmitate: dose mean 90 mg/IM/25 days. N=61. 
 2. Fluphenazine decanoate: dose mean 88 mg/IM/22 days. N=57. 
 3. Standard oral neuroleptics: dose (no further details). N=63.
Outcomes Global impression: CGI. 
 Mental state: BPRS. 
 Behaviour: NOSIE. 
 Leaving the study early. 
 Additional medication. 
 Adverse effects.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear