NCT00305071.

Study name	Effect of adjuvant treatment with compound cranberry extract tablets in acute bacterial cystitis
Methods	Double‐blind, placebo‐controlled RCT
Participants	60 females, 20‐65 years Inclusion criteria: female patient with non‐complicated acute bacterial cystitis Exclusion criteria: recent (less than one month) urinary tract infection, partially treated acute cystitis; anatomical or function disease of the lower urinary tract; patients received radical pelvic surgery; associated bladder stone disease; upper urinary tract anomaly or urolithiasis; systemic ‐ infection with body temperature higher than 38°C ‐ known allergic reaction to cranberry or vitamin C; pregnant or prepare to be pregnant
Interventions	Intervention group Will receive 3‐day oral trimethoprim/sulfamethoxazole (80/400 mg) 2 tablets twice a day on day 1 to 3 plus oral compound cranberry extract tablets (UmayC, 900 mg) 2 tablets three times a day on day 1 to 7 Control group Will received same oral antibiotics plus identical placebo prescribed as the same protocol of intervention arm. For patients with known allergic reaction to sulfa drug, the empirical antibiotics will be replaced by cephalexin (250 mg) 2 capsules four times a day.
Outcomes	Primary outcome measures Time to symptoms relief Secondary outcome measures Pyuria eradication rate
Starting date	April 2006
Contact information	Contact: Po‐Chien Huang, MD 886‐3‐3179599 ext 8223 m001435@e‐ms.com.tw Contact: Hung‐Ju Yang, MD 886‐3‐3179599 ext 8225 m001436@e‐ms.com.tw
Notes	Recruitment status at 21 March 2006: not yet recruiting No results published as at 18 August 2020