Comparison 2. Colloid (albumin) vs. crystalloid (saline) in hypotensive infants.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Death	2	164	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.50, 2.06]
2 Any P/IVH	2	119	Risk Ratio (M‐H, Fixed, 95% CI)	0.95 [0.56, 1.61]
3 P/IVH grade 3‐4	2	119	Risk Ratio (M‐H, Fixed, 95% CI)	0.77 [0.30, 1.95]
4 Failed treatment	2	163	Risk Ratio (M‐H, Fixed, 95% CI)	0.76 [0.54, 1.07]
5 Chronic lung disease	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 Oxygen at 28 days	1	63	Risk Ratio (M‐H, Fixed, 95% CI)	1.36 [0.48, 3.82]
5.2 Oxygen or CPAP at 36‐40 weeks	1	63	Risk Ratio (M‐H, Fixed, 95% CI)	1.94 [0.38, 9.83]
6 Patent ductus arteriosus	1	63	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.72, 1.61]
7 Necrotising enterocolitis	1	63	Risk Ratio (M‐H, Fixed, 95% CI)	1.94 [0.38, 9.83]
8 Sepsis	1	63	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
9 Change mean BP (%)	1	102	Mean Difference (IV, Fixed, 95% CI)	9.90 [1.22, 18.58]