| Methods |
Adequate randomisation: yes, sealed envelope.
Allocation concealment: yes.
Blinding of intervention: no.
Blinding of measurement: no.
Losses to follow‐up: none. |
| Participants |
Preterm infants day 1‐4 (23‐35 weeks, (552‐1954g), hypotension with systolic BP < 40 mmHg.
Exclusions: clinical fluid overload.
Median gestation: Group 1: 26 weeks (range 23‐34); Group 2: 27 weeks (range 24‐25). Median birthweight: Group 1: 958g (566‐1880). Group 2: 844g (690‐1954). |
| Interventions |
Intervention: Group 1 (n = 20) fresh frozen plasma 15 ml/kg over 3 hours.
Group 3 (n = 20) 4.5% albumin 15 ml/kg over 3 hours. |
| Outcomes |
Stated primary outcome: systolic BP one and 4 hours after infusions.
Other outcomes: none. |
| Notes |
No data available for inclusion in meta‐analysis.
Median change BP available. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Low risk |
A ‐ Adequate |
