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. 2004 Apr 19;2004(2):CD002055. doi: 10.1002/14651858.CD002055.pub2
Study Reason for exclusion
Alexander 1976 Fresh frozen plasma versus no treatment. Printed in abstract form only. Volume of fresh frozen plasma not stated. No clinical data could be extracted for inclusion in review.
Alkalay 1999 No control group.
Andrew 1993 Randomised trial of platelet transfusion in thrombocytopenic newborns.
Barr 1977 No control group.
Bauer 1993 No control group.
Beeram 2003 Randomised trial of two different volumes of packed red cell transfusions in haemodynamically stable very low birth weight infants.
Belgaumkar 1998 Retrospective cohort of 10 ml/kg 4.5% albumin infusion in 26 ventilated normotensive neonates with metabolic acidosis.
Bell 1980 Randomised trial of higher and lower fluid intakes.
Bignall 1989 No control group.
Bland 1976 Insufficient volume to meet inclusion criteria. Mean age of infants > 32 weeks. Randomised preterm infants < 37 weeks with serum protein < 4.6 g% to receive glucose versus albumin 25% 8 ml/kg within 2 hours of birth.
Blank 1984 Randomized to red cell transfusion to maintain Hb > 10 g/L or control group. Intervention predominantly late.
Chan 1976 Randomised to albumin 1g/kg versus no treatment prior to exchange transfusion.
Costarino 1992 Randomised trial of higher and low sodium intake.
Delivoria 1976 Used alternation to assign infants to exchange transfusion or control.
Dimitriou 2001 No control group. Observed effect of albumin infusion on BP, pH and core‐peripheral temperature difference.
Dixon 1999 Randomised trial of 10ml/kg 4.5% albumin versus 4.2% sodium bicarbonate in acidotic newborn infants. Gestations not reported. Infants with hypotension or evidence of acute blood loss excluded.
Ekblad 1987 Randomised to high and low sodium intake.
Greenough 1993 Given inadequate volume: 20% albumin 5 ml/kg given at maintenance fluid rate instead of maintenance fluids. Placebo was maintenance fluids.
Gurkan 2000 Randomised trial of 20% albumin 0.5g/kg in term newborns with perinatal asphyxia.
Hosono 2001 Randomised trial of albumin infusion in term infants with non‐haemolytic hyperbilirubinaemia.
Kanarek 1991 Randomised after 48‐72 hours of age to addition of albumin to total parenteral nutrition.
Kavvadia 2000 Trial of fluid restriction.
Lambert 1998 No control group.
Lay 1980 No control group.
Leake 1976 Infants 3 to 16 days age. Infants randomly assigned to different infusion rates of maintenance fluids.
Liet 2003 Neonates 690–4030g, gestational age 26–40 weeks without cardiac or renal failure or major hemostasis abnormalities and requiring a peripherally inserted central catheter for parenteral nutrition. Median (1st/3rd quartiles) age enrolment HES group: day 3 (3, 6); saline: day 5 (4, 6).
Liet 2006 Hypotensive preterm infants (mean gestational age of 29 +/‐3 week) randomly allocated to 10ml/kg 5% albumin versus isotonic saline versus hydroxyethyl starch (HES). Infants age at randomisation (days): albumin: 2+/‐1; saline: 6 +/‐10; HES: 5 +/‐ 6.
McMurray 1948 Insufficient volume: used 3ml 25g/dl albumin injected per pound bodyweight 1–2 times weekly versus no albumin. Given after day 3. Treatment allocation by alternation with process not strictly adhered to.
Meyer 1993 Randomised to packed red cell transfusion to maintain hematocrit > 0.35 or control. Mean time of transfusion 28 days
Nelle 1997 Enrolled preterm infants with anaemia. Studied effect of blood transfusion. No control group.
Nose 1996 Infants < 4 days old excluded. Randomised study of 2 different infusion rates of red cell transfusion.
Oca 2003 Enrolled 50 newborn infants with hypotension in first 24 hours. Stratified randomisation of infants <2500g and >=2500. Excluded because of excessive post randomisation losses (9/39 =23%) for infants <2500g.
Papile 1978 Observational study of effects of sodium bicarbonate in acidotic infants.
Paul 2002 Comparison of 10 versus 20 ml/kg red blood cells in infants <1500g. Mean postnatal age 23‐26 days.
Paul 2003 Enrolled infants aged 1–38 months, allocated randomly to 20 ml/kg HES 70/0.5 or Ringer's lactate during the first hour of urological surgery.
Pladys 1994 No control group.
Pladys 1997 No control group.
Sinclair 1968 Infants randomised to varying oxygen, alkali (rapid infusion of sodium bicarbonate) and ventilation strategies.
Sriram 1997 No control group.
Stoddart 1996 Enrolled neonates undergoing major surgery. They were excluded if the body weight was less than 2kg.
Upadhyay 2005 Enrolled infants with septic shock 1 month to 12 years age.
Warburton 1983 Randomised to different volumes of maintenance fluids.
Weisman 1992 Randomised infants with early onset sepsis to 10ml/kg intravenous immunoglobulin or albumin.
Wirth 1979 Control group received bicarbonate. Crossover study of bicarbonate and albumin. Gestational ages of infants not stated. Printed in abstract form only.
Wong 2005 Infants <1500g with HCT <0.30 randomised to 2 different red cell transfusion volumes.
Wright 1995 Unable to obtain data from author.