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. 2019 Apr 3;21(8):2913–2917. doi: 10.1021/acs.orglett.9b00946

Table 2. Cross-Coupling of Boronic Ester 2a with Different Alkenyl Ethers 1b–m.

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a

All reactions were carried out using 1b–m (0.27 mmol) and 2a (0.33 mmol, 120 mol %) in 1.4 mL of toluene. Yields were individually obtained after purification by column chromatography on silica gel. The E/Z ratio was determined by 1H NMR spectroscopic analysis of the unpurified mixture of products.

b

Reaction was carried out at 105 °C.

c

Reaction was carried out using Ni(acac)2 (20 mol %), DIBAL (40 mol %), and PCy3 (60 mol %) in 1.4 mL of toluene at 105 °C.