. Author manuscript; available in PMC: 2020 Feb 17.

Published in final edited form as: Psychiatr Clin North Am. 2016 Mar;39(1):139–155. doi: 10.1016/j.psc.2015.10.004

Table 2.

Copy number variations (CNV) nominal significance (P<.05) for association with BD

CNV Locus	Odds Ratio^a	P-Value	Frequency Cases	Frequency Controls
1q21.1 duplication	2.6	.02	0.099% (8/8084)	0.037% (24/64,046)
3q29 deletion	17.3	.03	0.025% (2/8084)	0.0014% (1/69,965)
16p11.2 duplication	4.4	2.3 ×10⁻⁴	0.13% (12/9129)	0.03% (19/63,068)

Abbreviation: CNV, copy number variation.

Effect estimates and raw numbers obtained from the meta-analysis performed by Green and colleagues.

Data from Green EK, Rees E, Walters JT et al. Copy number variation in bipolar disorder. Mol Psychiatry 2015;[Epub ahead of print].