Table 3. PANTHER protein class differentially expressed in P7 Tgfbr2;ScxCre mutant cells compared with P7 wild-type tenocytes.
A complete list of differentially expressed genes (≥2 fold change, adjusted p<0.05) used for the analysis is available in Supplementary file 2.
| (A) Downregulated protein class | |
|---|---|
| Protein class | Gene list |
| Receptor | Pdgfrl, Col6a3, Kdelr3, Col6a1, Kdelr2, Itgbl1, Ssc5d, Col6a2, Ssr4, Col12a1, Matn4 |
| Signaling molecule | Sdc1, Wisp1, Sparc, Mfap4, Sema3b, Angptl2, Tgfbi |
| Membrane traffic protein | Sec13, Kdelr3, Copz2, Kdelr2, Rabac1, Lman1 |
| Extracellular matrix protein | Sdc1, Crtap, Clec11a, P3h3, Sparc, P3h4 |
| (B) Upregulated protein class | |
| Protein class | Gene list |
| Nuclei acid binding | Ndn, Eif3f, Rpl39, Rpl36a, Rpl3, Rpl9-ps6, Rpl22l1, Rps27, Rps4x, Cirbp, Rps19, Eif3e, Rps18, Rps5, Junb |
| Enzyme modulator | Fstl1, Dbi, Sfrp2, Ctsb, Serpine2, Serping1, Igfbp3, Igfbp4 |
| Cytoskeletal protein | Gsn, Map1lc3b, Tuba1b, Arpc1b, Emp1, Tubb5 |
| Signaling molecule | S100a16, Ptn, Dlk1, Efemp2, Postn, Sfrp2 |
| Transcription factor | Eif3h, Naca, Fos, Id3, Junb |