Table 4. PANTHER pathway analysis of upregulated genes in P7 Tgfbr2;ScxCre mutant cells compared with P7 wild-type tenocytes.

PANTHER pathway	PANTHER accession	Gene list
Integrin signaling pathway	P00034	Arpc2, Col4a1, Rac1, Col5a2, Rap1b, Cdc42, Arpc5, Col5a1, Rap1a, Rhoc, Fn1, Arpc1b, Col3a1
Inflammation mediated by chemokine and cytokine signaling pathway	P00031	Arpc2, Rac1, Cdc42, Nfkbia, Arpc5, Rhoc, Arpc1b, Arpc4, Jun, Junb
Wnt signaling pathway	P00057	Fstl1, Sfrp2, Ppp3ca, Csnk1a1
Insulin/IGF pathway	P00032, P00033	Igf1, Igf2, Fos

Note:.

¹A complete list of differentially expressed genes (DEGs) used for the analysis is available in Supplementary file 2.

²Different values of the filter parameter (mean UMI count and fold change) were applied for enriching DEGs in P7 mutant cells. Only pathways that stood out as relevant for this study are listed.