Table 3.
Univariate analyses of risk factors with respective odds ratios for the development of post-CBA atrial flutter, comparing patients who developed atrial flutter after blanking period (n = 25) and those who did not develop post-CBA-PVI atrial flutter (n = 513)
| OR | 95% CI | p value | |
|---|---|---|---|
| Male gender | 1.24 | 0.51–3.03 | 0.64 |
| Age > 65 years old | 0.77 | 0.32–1.78 | 0.52 |
| Body mass index > 28 kg/m2 | 1.01 | 0.45–2.26 | 0.97 |
| NYHA class ≥ 2 | 5.02 | 2.05–12.28 | < 0.01 |
| Left ventricular ejection fraction <50% | 3.36 | 1.39–8.11 | < 0.01 |
| Bundle branch block | 4.33 | 1.51–12.40 | < 0.01 |
| Non-paroxysmal atrial fibrillation | 1.69 | 0.75–3.84 | 0.21 |
| Left atrial diameter ≥ 47 mm | 1.89 | 0.68–5.22 | 0.22 |
| Glomerular filtration rate < 60 mL/min/1.73 m2 | 1.21 | 0.35–4.18 | 0.76 |
| History of RFA-PVI | 2.68 | 1.03–7.01 | 0.04 |
| Late recurrence of atrial fibrillation (> 3 months after CBA) | 4.76 | 2.08–10.86 | < 0.01 |
Statistical significance defined by p < 0.05
NYHA New York Heart Association, CBA cryoballoon ablation