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. 2020 Jan 10;35(6):e40. doi: 10.3346/jkms.2020.35.e40

Table 2. Clinical responses to tocilizumab at weeks 24 and 48.

Efficacy measure 25(OH)D ≥ 30 ng/mL (n = 34) 25(OH)D < 30 ng/mL (n = 64) P value
At week 24
DAS28 reduction, % 64.6 ± 15.5 52.7 ± 20.7 0.004
Low DAS28 (DAS28 ≤ 3.2) 31 (91.2) 45 (70.3) 0.018
Remission (DAS28 ≤ 2.6) 28 (82.4) 37 (57.8) 0.014
Clinically significant reduction ≥ 1.2 33 (97.1) 59 (92.2) 0.661
At week 48 (n = 25) (n = 50)
DAS28 reduction, % 67.6 ± 13.9 59.8 ± 16.4 0.044
Low DAS28 (DAS28 ≤ 3.2) 24 (96.0) 43 (86.0) 0.256
Remission (DAS28 ≤ 2.6) 23 (92.0) 35 (70.0) 0.032
Clinically significant reduction ≥ 1.2 25 (100.0) 49 (98.0) 1.000

Data are presented as number (%) or mean ± standard deviation.

DAS = disease activity score.