Table 2. Clinical responses to tocilizumab at weeks 24 and 48.
Efficacy measure | 25(OH)D ≥ 30 ng/mL (n = 34) | 25(OH)D < 30 ng/mL (n = 64) | P value | |
---|---|---|---|---|
At week 24 | ||||
DAS28 reduction, % | 64.6 ± 15.5 | 52.7 ± 20.7 | 0.004 | |
Low DAS28 (DAS28 ≤ 3.2) | 31 (91.2) | 45 (70.3) | 0.018 | |
Remission (DAS28 ≤ 2.6) | 28 (82.4) | 37 (57.8) | 0.014 | |
Clinically significant reduction ≥ 1.2 | 33 (97.1) | 59 (92.2) | 0.661 | |
At week 48 | (n = 25) | (n = 50) | ||
DAS28 reduction, % | 67.6 ± 13.9 | 59.8 ± 16.4 | 0.044 | |
Low DAS28 (DAS28 ≤ 3.2) | 24 (96.0) | 43 (86.0) | 0.256 | |
Remission (DAS28 ≤ 2.6) | 23 (92.0) | 35 (70.0) | 0.032 | |
Clinically significant reduction ≥ 1.2 | 25 (100.0) | 49 (98.0) | 1.000 |
Data are presented as number (%) or mean ± standard deviation.
DAS = disease activity score.