Table 2.
Intervention versus control attrition rates at the end of the trial intervention
| Treatment | No. of trials | Pooled attrition OR (95% CI) | Time-point specific heterogeneity | Overall heterogeneity P-value |
|---|---|---|---|---|
| CBT | ||||
| 6-months | 5 | 1.06 (0.76–1.49) | 0.0%; p=0.99 | 0.99 |
| 12-months | 5 | 1.02 (0.74–1.42) | 0.0%; p=0.77 | |
| 24-months | 3 | 0.87 (0.62–1.22) | 0.0%; p=0.98 | |
| CRT | ||||
| 2-months | 3 | 0.85 (0.39–4.89) | 0.0%; p=0.38 | - |
| Interpersonal therapies | ||||
| 12-months | 2 | 1.06 (0.38–2.98) | 42.6%; p=0.19 | 0.51 |
| 24-months | 3 | 0.77 (0.46–1.29) | 0.0%; p=0.63 | |
| Omega-3 | ||||
| 6-months | 3 | 1.07 (0.71–1.61) | 0.0%; p=0.75 | 0.35 |
| 12-months | 3 | 1.53 (0.68–3.43) | 0.0%; p=0.07 | |
Abbreviations: CBT=cognitive behavioural therapy; CI=confidence interval; CRT=cognitive remediation therapy; NMDAR=N-Methyl-D-Aspartic acid receptor; OR=odds ratio