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. 2019 Nov 13;105(3):e651–e659. doi: 10.1210/clinem/dgz199

Table 3.

Serum Uric Acid at 1 Year Postpartum and Change in Uric Acid Between 1 and 3 Years Postpartum as Predictors of the Following Metabolic Outcomes at 3 Years Postpartum: (1) Matsuda Index, (2) HOMA-IR, (3) ISSI-2, (4) Insulinogenic Index/HOMA-IR, (5) Fasting Glucose, and (6) 2-Hour Glucose.

Outcome at 3 Years Predictor Beta T P
Log Matsuda index Uric acid at 1 year –0.001031 –1.82 0.07
Change in uric acid from 1 to 3 years –0.001190 –1.57 0.12
Log HOMA-IR Uric acid at 1 year 0.000430 0.70 0.48
Change in uric acid from 1 to 3 years 0.000160 0.20 0.84
ISSI-2 Uric acid at 1 year –0.545933 –1.37 0.17
Change in uric acid from 1 to 3 years –0.266129 –0.50 0.62
Log IGI/HOMA-IR Uric acid at 1 year –0.002011 –1.83 0.07
Change in uric acid from 1 to 3 years –0.000984 –0.69 0.49
Fasting glucose Uric acid at 1 year –0.000433 –0.76 0.45
Change in uric acid from 1 to 3 years –0.001083 –1.43 0.15
2-hour glucose Uric acid at 1 year 0.002975 1.45 0.15
Change in uric acid from 1 to 3 years 0.002460 0.90 0.37

Each model was adjusted for age, ethnicity, family history of diabetes, duration of breastfeeding, BMI at 1 year, change in BMI from 1 to 3 years, and the baseline measure of the respective outcome variable at 1 year postpartum.

Abbreviations: BMI, body mass index; HOMA-IR, homeostasis model assessment-insulin sensitivity/resistance; ISSI, insulin secretion-sensitivity index-2.