Table 3.
Serum Uric Acid at 1 Year Postpartum and Change in Uric Acid Between 1 and 3 Years Postpartum as Predictors of the Following Metabolic Outcomes at 3 Years Postpartum: (1) Matsuda Index, (2) HOMA-IR, (3) ISSI-2, (4) Insulinogenic Index/HOMA-IR, (5) Fasting Glucose, and (6) 2-Hour Glucose.
| Outcome at 3 Years | Predictor | Beta | T | P |
|---|---|---|---|---|
| Log Matsuda index | Uric acid at 1 year | –0.001031 | –1.82 | 0.07 |
| Change in uric acid from 1 to 3 years | –0.001190 | –1.57 | 0.12 | |
| Log HOMA-IR | Uric acid at 1 year | 0.000430 | 0.70 | 0.48 |
| Change in uric acid from 1 to 3 years | 0.000160 | 0.20 | 0.84 | |
| ISSI-2 | Uric acid at 1 year | –0.545933 | –1.37 | 0.17 |
| Change in uric acid from 1 to 3 years | –0.266129 | –0.50 | 0.62 | |
| Log IGI/HOMA-IR | Uric acid at 1 year | –0.002011 | –1.83 | 0.07 |
| Change in uric acid from 1 to 3 years | –0.000984 | –0.69 | 0.49 | |
| Fasting glucose | Uric acid at 1 year | –0.000433 | –0.76 | 0.45 |
| Change in uric acid from 1 to 3 years | –0.001083 | –1.43 | 0.15 | |
| 2-hour glucose | Uric acid at 1 year | 0.002975 | 1.45 | 0.15 |
| Change in uric acid from 1 to 3 years | 0.002460 | 0.90 | 0.37 |
Each model was adjusted for age, ethnicity, family history of diabetes, duration of breastfeeding, BMI at 1 year, change in BMI from 1 to 3 years, and the baseline measure of the respective outcome variable at 1 year postpartum.
Abbreviations: BMI, body mass index; HOMA-IR, homeostasis model assessment-insulin sensitivity/resistance; ISSI, insulin secretion-sensitivity index-2.