Table 5.
Serum uric acid at 1 Year Postpartum and Change in Uric Acid Between 1 and 3 Years Postpartum as Predictors of the Indicated Metabolic Outcomes at 3 Years Postpartum in Women in Whom Uric Acid Increased Between 1 and 3 Years (n = 123).
Outcome at 3 Years | Predictor | Beta | T | P |
---|---|---|---|---|
Log Matsuda index | Uric acid at 1 year | –0.001492 | –1.79 | 0.08 |
Change in uric acid from 1 to 3 years | 0.003319 | 1.62 | 0.11 | |
Log HOMA-IR | Uric acid at 1 year | 0.000716 | 0.77 | 0.44 |
Change in uric acid from 1 to 3 years | –0.003485 | –1.55 | 0.12 | |
ISSI-2 | Uric acid at 1 year | –0.500765 | –0.93 | 0.35 |
Change in uric acid from 1 to 3 years | –1.370566 | –1.03 | 0.30 | |
Log IGI/HOMA-IR | Uric acid at 1year | –0.001200 | –0.81 | 0.42 |
Change in uric acid from 1 to 3 years | –0.005490 | –1.57 | 0.12 | |
Fasting glucose | Uric acid at 1 year | –0.000446 | –0.49 | 0.62 |
Change in uric acid from 1 to 3 years | –0.001579 | –0.73 | 0.47 | |
2-hour glucose | Uric acid at 1 year | 0.005240 | 1.64 | 0.10 |
Change in uric acid from 1 to 3 years | –0.000211 | –0.03 | 0.98 |
Each model was adjusted for age, ethnicity, family history of diabetes, duration of breastfeeding, BMI at 1 year, change in BMI from 1 to 3 years, and the baseline measure of the respective outcome variable at 1 year postpartum.
Abbreviations: BMI, body mass index; IGI, insulinogenic index; HOMA-IR, homeostasis model assessment-insulin resistance; ISSI-2, insulin secretion-sensitivity index-2.