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. 2019 Nov 13;105(3):e651–e659. doi: 10.1210/clinem/dgz199

Table 6.

Serum Uric Acid at 1 Year Postpartum and Change in Uric Acid Between 1 and 3 Years Postpartum as Predictors of the Indicated Metabolic Outcomes at 3 Years Postpartum in Women Who Did Not Have GDM (n = 203).

Outcome at 3 Years Predictor Beta T P
Log Matsuda index Uric acid at 1 year –0.001039 –1.46 0.15
Change in uric acid from 1 to 3 years –0.001084 –1.18 0.24
Log HOMA-IR Uric acid at 1 year 0.000775 1.00 0.32
Change in uric acid from 1 to 3 years 0.000679 0.69 0.49
ISSI-2 Uric acid at 1 year –0.512043 –1.02 0.31
Change in uric acid from 1 to 3 years –0.422132 –0.65 0.52
Log IGI/HOMA-IR Uric acid at 1 year –0.001535 –1.14 0.26
Change in uric acid from 1 to 3 years –0.001920 –1.13 0.26
Fasting glucose Uric acid at 1 year –0.000556 –0.82 0.42
Change in uric acid from 1 to 3 years –0.000195 –0.22 0.82
2-hour glucose Uric acid at 1 year 0.001070 0.43 0.67
Change in uric acid from 1 to 3 years 0.001168 0.37 0.71

Each model was adjusted for age, ethnicity, family history of diabetes, duration of breastfeeding, BMI at 1 year, change in BMI from 1 to 3 years, and the baseline measure of the respective outcome variable at 1 year postpartum.

Abbreviations: BMI, body mass index; GDM, gestational diabetes mellitus; HOMA-IR, homeostasis model assessment-insulin resistance; IGI, insulinogenic index; ISSI-2, insulin secretion-sensitivity index-2.