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Baicalin alters the gene expression of hepatic enzymes involved in bile acid (BA) metabolism in rats. (A) The mRNA expression of BA synthetic enzymes, Cyp7a1, Cyp8b1, and Cyp27A1. (B) The mRNA expression of BA metabolism enzymes, Cyp3a2, Bal, Baat, and Sult2a1. (C) The protein levels of CYP7A1 and CYP27A1. Data are presented as the mean ± SD (n = 6). *p < 0.05 and **p < 0.01 versus the control group, #p < 0.05 and ##p < 0.01 versus the EE group.
