Table 2.
Measure | 33 Weeks | 2 Weeks | 6 Weeks | 16 Weeks | ||||
---|---|---|---|---|---|---|---|---|
Early | Late | Early | Late | Early | Late | Early | Late | |
Sleep and circadian measures | ||||||||
Sleep onset (clock time ± minutes) | 10:38 p.m. ± 35 | 12:33 a.m. ± 46* | 11:07 p.m. ± 56 | 12:10 a.m. ± 65* | 11:11 p.m. ± 62 | 12:17 p.m. ± 62* | 10:58 p.m. ± 53 | 12:13 a.m. ± 69* |
Sleep offset (clock time ± min) | 7:31 a.m. ± 64 | 8:29 a.m. ± 78* | 7:43 a.m. ± 59 | 9:03 a.m. ± 82* | 7:49 a.m. ± 64 | 8:52 a.m. ± 73* | 7:04 a.m. ± 55 | 8:00 a.m. ± 79* |
Time in bed (min) | 524 ± 41 | 477 ± 68* | 517 ± 54 | 534 ± 65 | 507 ± 74 | 516 ± 56 | 488 ± 56 | 468 ± 75 |
Estimated sleep duration (min) | 439 ± 73 | 385 ± 71* | 369 ± 62 | 372 ± 52 | 384 ± 57 | 375 ± 57 | 406 ± 53 | 379 ± 66 |
Sleep efficiency (%) | 84.5 ± 11.0% | 82.0 ± 7.6% | 73.0 ± 7.1% | 71.3 ± 7.1% | 77.6 ± 6.9% | 74.1 ± 7.5% | 84.4 ± 6.3% | 81.9 ± 7.6% |
DLMO (clock time ± min) | 9:05 p.m. ± 74 | 9:46 p.m. ± 88 | 9:31 p.m. ± 80 | 10:05 p.m. ± 93 | ||||
Phase angle (h) | 1.5 ± 1.0 | 2.7 ± 1.2* | 1.6 ± 1.2 | 2.0 ± 1.1 | ||||
Transdiagnostic symptoms | ||||||||
Highs | 1.40 ± 1.63 | 2.19 ± 2.0 | 0.92 ± 1.32 | 2.31 ± 2.09* | 1.16 ± 1.70 | 1.88 ± 2.29 | 1.33 ± 1.95 | 2.00 ± 1.84 |
OCI | 14.28 ± 19.75 | 18.37 ± 21.01 | 14.00 ± 21.98 | 18.04 ± 23.45 | ||||
HAM-D17 | 5.88 ± 3.11 | 6.69 ± 3.58 | 6.08 ± 3.00 | 9.35 ± 5.61* | 6.96 ± 3.98 | 9.04 ± 5.15 | 6.79 ± 4.18 | 9.21 ± 8.26 |
Sleep measures were collected by actigraphy during each study week, and circadian measures were determined using salivary dim light melatonin onset measured at week 33 of pregnancy and week 6 postpartum. Hypomanic/manic symptoms were measured with the Highs scale. Obsessive-compulsive symptoms were measured with the Obsessive-Compulsive Inventory (OCI). Depressive symptoms were measured with the 17-item Hamilton Rating Scale for Depression (HAM-D17)
*p < 0.05, showing when the “late sleep” group was significantly different compared with the “early sleep” group