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. 2020 Feb 17;3:77. doi: 10.1038/s42003-020-0803-x

Fig. 2. Mechanism of resistance for polymyxin antibiotics conferred by mcr-1.

Fig. 2

a General mode of polymyxin activity, and b biophysical mechanism of action for polymyxin-induced membrane damage in general membranes, as described in Khondker et al.11. mLipid A is modified lipid A.