Table 2.

Association of cognition and psychopathology in children and adolescents with 22q11.2DS relative to typically developing controls.

	Probable ASD						ADHD						Anxiety Disorder
	Main effect on measure			Interaction with developmental stage			Main effect on measure			Interaction with developmental stage			Main effect on measure			Interaction with developmental stage
	F (df)	p	Effect size; η²	F (df)	p	Effect size; η²	F (df)	p	Effect size; η²	F (df)	p	Effect size; η²	F (df)	p	Effect size; η²	F (df)	p	Effect size; η²
Neuro-cognitive scores
Processing speed	0.59 (1,107)	0.443	0.01	5.45 (1,107)	0.021a	0.05	2.13 (1,107)	0.147	0.019	1.89 (1,107)	0.172	0.02	0.01 (1,109)	0.916	0	0.44 (1,109)	0.507	0
Sustained attention	2.11 (1,98)	0.149	0.02	5.42 (1,98)	0.022	0.05	8.85 (1,98)	0.004	0.082	1.61 (1,98)	0.207	0.02	0.02 (1,100)	0.891	0	0.03 (1,100)	0.86	0
Working memory	0.18 (1,116)	0.669	0	8 (1,116)	0.006	0.06	2.39 (1,117)	0.125	0.019	0.03 (1,117)	0.865	0	2.29 (1,119)	0.133	0.02	0.76 (1,119)	0.385	0.01
IQ test scores
Full-scale IQ	0.53 (1,114)	0.468	0.01	0.54 (1,114)	0.463	0.01	0 (1,115)	0.954	0	2.75 (1,115)	0.1	0.02	0.55 (1,117)	0.46	0.01	0.01 (1,117)	0.905	0
Verbal IQ	1.82 (1,114)	0.18	0.02	0.13 (1,114)	0.723	0	0.08 (1,115)	0.78	0.001	2.46 (1,115)	0.12	0.02	1.46 (1,117)	0.229	0.01	0 (1,117)	0.971	0
Performance IQ	0 (1,116)	0.957	0	1.3 (1,116)	0.257	0.01	0.28 (1,117)	0.598	0.002	2.17 (1,117)	0.143	0.02	0.02 (1,119)	0.891	0	0.19 (1,119)	0.665	0

ASD autism spectrum disorder, ADHD attention deficit hyperactivity disorder.

^aDenotes comparison that did not survive multiple comparison correction.

p values that are statistically significant are shown in bold.