Table 3.
Comparisons among the RBANS total and five domain scores by diagnostic and genotypic groups.
| RBANS scores | Patients with schizophreniaa | Controls | Diagnosis | Genotype | Diagnosis X genotype | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| TT (N = 544) |
TC + CC (N = 81) |
TT (N = 347) |
TC + CC (N = 53) |
F | p | F | p | F | p | |
| Immediate memory | 56.28 ± 15.10 | 54.24 ± 15.65 | 76.02 ± 17.07 | 74.06 ± 20.33 | 167.34 | <0.001 | 1.71 | 0.19 | 0.001 | 0.98 |
| Attention | 61.83 ± 17.70a | 57.70 ± 13.08a | 87.87 ± 20.26 | 84.47 ± 21.43 | 226.60 | <0.001 | 4.60 | 0.03b | 0.04 | 0.87 |
| Language | 73.42 ± 17.54 | 70.54 ± 16.70 | 94.15 ± 12.98 | 92.85 ± 13.96 | 203.97 | <0.001 | 1.92 | 0.17 | 0.28 | 0.60 |
| Visuospatial/construction | 75.02 ± 17.50 | 71.70 ± 15.94 | 80.08 ± 15.89 | 78.06 ± 13.73 | 13.09 | <0.001 | 2.88 | 0.09 | 0.18 | 0.68 |
| Delayed memory | 61.99 ± 18.37 | 61.96 ± 18.09 | 86.54 ± 14. 93 | 85.06 ± 17.48 | 213.15 | 0.001 | 0.21 | 0.64 | 0.20 | 0.66 |
| Total score | 59.12 ± 13.38 | 56.64 ± 11.35 | 80.41 ± 15.02 | 78.30 ± 16.70 | 261.71 | <0.001 | 2.98 | 0.08 | 0.02 | 0.89 |
| BMI | 23.97 ± 4.52 | 23.99 ± 4.00 | 25.10 ± 4.20 | 25.50 ± 4.64 | 10.00 | 0.002 | 0.25 | 0.62 | 0.20 | 0.66 |
aA significant genotypic effect on Attention score in patients with schizophrenia.
bThere was a significant genotype effect on Attention score in all subjects (F = 4.60, p = 0.03). Patients carrying TC + CC had lower attention score than those carrying CC in patient group (adjusted F = 4.77, p = 0.029). There was no difference in attention score between controls carrying TC + CC and carrying CC (adjusted F = 0.20, p = 0.66).