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. 2020 Feb 17;10:2757. doi: 10.1038/s41598-020-59671-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relationship among residual tumor at the time of surgery, HRD status, and prognosis. (A) The 514 cases were sorted by size of the residual tumor if data on residual tumor at the time of surgery were available (no macroscopic disease, 1–10 mm and >10 mm) and their survival rates were compared. (B) Cases with residual tumor ≥1 mm and available SNP array data were divided into the HRD and non-HRD groups. HRD cases with exome sequencing data were further sorted by molecular mechanism into genetic HRD, epigenetic HRD, and undetermined HRD to compare the survival rate. (C) Similarly, cases with no macroscopic disease were classified by the HRD status for survival rate comparison.