Table 4.
Importance of each biological process from random forest in classifying ASD subjects into defined phenotypic clusters.
| Random Forest rank | Biological process | Mean decrease in accuracy |
|---|---|---|
| 1 | Regulation of cellular component organization | 0.052 |
| 2 | Cell projection organization | 0.025 |
| 3 | Cellular component assembly | 0.025 |
| 4 | Single-organism behavior | 0.020 |
| 5 | Organelle organization | 0.018 |
| 6 | Single-organism organelle organization | 0.017 |
| 7 | Cellular component biogenesis | 0.014 |
| 8 | Cognition | 0.013 |
| 9 | Nervous system development | 0.010 |
| 10 | Cellular localization | 0.009 |
| 11 | Cellular component organization | 0.006 |
| 12 | Protein polyubiquitination | 0.005 |
| 13 | Homophilic cell adhesion via plasma-membrane adhesion molecules | 0.005 |
| 14 | Cell adhesion via plasma-membrane adhesion molecules | 0.005 |
| 15 | Cellular component organization or biogenesis | 0.003 |