Table 2.
Generalised summary-data-based Mendelian randomisation (GSMR) results.
| Outcome | Exposure | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| DC1 | DC1 | ||||||||
| Exposure | b | s.e. | p | NSNP | Outcome | b | s.e. | p | NSNP |
| Schizophreniaa | −0.03 | 0.00 | 2.0E-02 | 118 | Schizophrenia | 0.98 | 0.16 | 8.9E-01 | 24 |
| Anorexia Nervosa | n/a | n/a | n/a | n/ab | Anorexia Nervosaa | 0.49 | 0.38 | 6.0E-01 | 26 |
| Waist hip ratio | −0.01 | 0.02 | 6.4E-01 | 31 | Waist hip ratio | 0.06 | 0.06 | 3.2E-01 | 21 |
| DC2 | DC2 | ||||||||
| b | s.e. | p | NSNP | b | s.e. | p | NSNP | ||
| Schizophreniaa | 0.05 | 0.00 | 3.2E-06 | 118 | Schizophreniaa | 1.43 | 0.10 | 1.0E-03 | 46 |
| Bipolara | 0.05 | 0.01 | 6.0E-03 | 16 | Bipolara | 1.92 | 0.13 | 3.3E-07 | 46 |
| Intelligence | −0.04 | 0.02 | 5.0E-02 | 13 | Intelligence | −0.08 | 0.06 | 2.0E-01 | 38 |
| Age at Menarche | −0.01 | 0.01 | 1.7E-01 | 71 | Age at Menarche | −0.18 | 0.06 | 2.0E-03 | 45 |
| Chronotypea | 0.08 | 0.03 | 1.6E-01 | 11 | Chronotypea | 1.07 | 0.04 | 7.0E-02 | 50 |
| BMI | 0.15 | 0.01 | 4.8E-39 | 82 | BMI | 0.07 | 0.04 | 6.0E-02 | 44 |
DC diet component, NSNP number of single-nucleotide polymorphisms, b; abeta coefficient on the liability scale, in bold are statistically significant associations.