Table 3.

Biochemical assay in serum (Data presented as mean ± SD, n = 6).

Parameters	PBS	pGO	pGO-Pt/DOX	Pt/DOX
ALT (alanine aminotransferase) (U/L)	6.8 ± 6.6	38.6 ± 13.0	39.6 ± 5.9	45.6 ± 11.3
AST (aspartate aminotransferase) (U/L)	147 ± 28	143 ± 26	164.6 ± 23	147 ± 51
ALP (alkaline phosphatase) (U/L)	70.6 ± 9.5	72.2 ± 22.8	74.2 ± 17.3	74.2 ± 19.1
BUN (blood urea nitrogen) (mmol/L)	7.7 ± 1.9	8.8 ± 4.2	9.6 ± 3.8	24.4 ± 8.9*
CK (creatine kinase) (U/L)	452 ± 60	479 ± 70	439 ± 111	627 ± 106*
LDH (lactate dehydrogenase) (U/L)	491 ± 66	498 ± 85	478 ± 118	652 ± 165*