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. 2020 Jan 22;10:25. doi: 10.1038/s41398-020-0719-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Immunoblots and quantification of H3K27me3, H3K4me2, and H3K4me3 levels in the hippocampus of adult rats. b Immunostaining of H3K27me3 (green) and nucleus (blue) in DG region of adult rats hippocampus. The scale bar represents 50 μm. c Immunoblots and quantification of EZH2 levels in the hippocampus of adolescent rats. Ctrl non-treated rats, Pb lead-treated rats, Pb+prob lead and probiotics-treated rats, prob probiotics-treated rats. The data are represented as mean ± SEM; ***p < 0.001, **p < 0.01, *p < 0.05.