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. 2018 Oct 15;30(1):3–44. doi: 10.1007/s00198-018-4704-5

Table 12.

Contrasting effects on the number of fractures saved with an intervention, the efficacy of which the relative risk reduction (RRR) is independent or dependent on FRAX (average RRR set at 40%)

FRAX independent FRAX dependent
Fracture probability (%) RRR (%) Fractures saved RRR (%) Fractures saved
0 40 0 0 0
5 40 2 0.14 1
10 40 4 0.27 3
15 40 6 0.40 6
20 40 8 0.54 11
25 40 10 0.68 17
30 40 12 0.80 24
Total 42 62