Fig. 6.

Kaplan–Meier survival curves of rats treated with central infusions of saline (CST, gray line, n = 25) and central infusions of donepezil for 120 days (CDT, black line, n = 25). Treatments were started 14 days post-myocardial infarction (MI). a Survival free from all-cause deaths in the CDT group significantly improved compared to the CST group (68% vs. 32%, P = 0.002). The median survival in the CST group was 99 days and was 181 days in the CDT group. b There were no differences in survival free from sudden cardiac deaths between the CDT and CST groups (80% vs. 70%, P = 0.399). c CDT markedly increased survival free from pump failure deaths (80% vs. 40%, P = 0.006). Vertical tick marks showed censored rats by pump failure death (in b) or sudden cardiac death (in c)