Table 4.
Patients’ demographic characteristics in relation to grade of background gastric mucosal atrophy at eradication therapy
| Total | Gastric mucosal atrophya | |||
|---|---|---|---|---|
| Mild | Moderate | Severe | ||
| N = 2737 | N = 801 | N = 1090 | N = 846 | |
| Ageb | 53.8 ± 9.1 | 50.6 ± 9.1 | 53.7 ± 8.7 | 57.0 ± 8.5 |
| Genderc | ||||
| M | 2193 | 629 | 844 | 720 |
| F | 544 (19.9%) | 172 (21.5%) | 246 (22.6%) | 126 (14.9%) |
| Drinkingd | ||||
| Absence | 1189 | 348 | 495 | 346 |
| Presence | 1548 (56.6%) | 453 (56.6%) | 595 (54.6%) | 500 (59.1%) |
| Smokingd | ||||
| Absence | 1390 | 410 | 554 | 426 |
| Presence | 1347 (49.2%) | 391 (48.8%) | 536 (49.2%) | 420 (49.6%) |
| Peptic ulcere | ||||
| Absence | 538 | 95 | 200 | 243 |
| Presence | 2199 (80.3%) | 706 (88.1%) | 890 (81.7%) | 603 (71.3%) |
aGastric mucosal atrophy was evaluated according to the endoscopic-atrophic-border scale as described in the text
bIn the linear regression analysis with age as the response variable and gastric mucosal atrophy as the explanatory variable using mild atrophy as a reference, the regression coefficient (95% confidence interval) was 3.11 (2.31–3.90, P < 0.001) in moderate atrophy and 6.43 (95% 5.59–7.28, P < 0.001) in severe atrophy
cFemale gender was less common in patients with severe atrophy than those with mild or moderate atrophy (P < 0.01, Chi-square test, residual analysis)
dSmoking or drinking habit was not significantly different among the patients’ groups
ePeptic ulcer diseases were less common in patients with severe atrophy than those with mild or moderate atrophy (P < 0.01, Chi-square test, residual analysis)