Table 2.
Analysis for preoperative variables associated with resectability of type IV HC patients
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Resectable group (n = 207) | Unresectable group (n = 81) | p value | HR (95% CI) | p value | |
| Gender | 0.486 | ||||
| Male | 159 | 104 | |||
| Female | 94 | 53 | |||
| Age (years) | 0.323 | ||||
| < 70 | 215 | 127 | |||
| ≥ 70 | 39 | 30 | |||
| CA-199 (U/mL) | < 0.001 | 1.970 (1.149–3.378) | 0.014 | ||
| ≤ 200 | 106 | 37 | |||
| > 200 | 148 | 120 | |||
| Total bilirubin (μmol/L) | 206.72 ± 172.05 | 253.90 ± 140.60 | 0.004 | 1.001 (0.999–1.002) | 0.450 |
| Albumin (g/L) | 0.754 | ||||
| ≤ 40 | 188 | 114 | |||
| > 40 | 66 | 43 | |||
| BMI | 0.038 | 1.584 (0.944–2.659) | 0.082 | ||
| ≤ 21 | 100 | 46 | |||
| > 21 | 154 | 111 | |||
| ASA score | 0.686 | ||||
| 1 | 6 | 6 | |||
| 2 | 140 | 84 | |||
| 3 | 108 | 67 | |||
| Pre-NLR | 0.041 | 1.517 (0.900–2.556) | 0.117 | ||
| < 3 | 183 | 98 | |||
| ≥ 3 | 71 | 59 | |||
| Pre-LMR | < 0.001 | 0.181 (0.111–0.296) | < 0.001 | ||
| ≤ 3.67 | 62 | 105 | |||
| > 3.67 | 192 | 52 | |||
| Tumor size (cm) | < 0.001 | 6.218 (3.705–10.435) | < 0.001 | ||
| ≤ 3 | 212 | 69 | |||
| > 3 | 42 | 88 | |||
| Portal vein embolization | |||||
| Yes | 17 | 7 | 0.348 | ||
| No | 237 | 150 | |||
The Italic emphasis (originally boldfaced) in Tables 2 and 3 specified the variables that were statistically significant in the univariate and multivariate logistic regression analysis (two-tailed P values < 0.05)