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. 2019 Sep 12;48(3):1056–1067. doi: 10.1093/nar/gkz783

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Translational bypassing. (A) Schematic of gene 60 mRNA. The nascent peptide, the SL element upstream (5′ SL) and downstream (3′ SL) of the take-off site, as well as the take-off SL are key elements facilitating bypassing. (B) Structure of the nascent peptide in the exit tunnel of the ribosome (left panel) and of the short A-site SL (right panel) obtained by cryo-EM (133). Middle panel represents a cartoon of the ribosome at the take-off site. (C) Schematic of bypassing. For details, see text. Rotation of the SSU relative to the LSU is indicated by different shades of blue. The blurred cartoon represents the ribosome in motion.