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Regions with poor gRNA coverage and functionally conserved residues in RPS12. Functionally important aa residues are underlined (72). Pipes (|) indicate Watson/Crick base pairs and colons (:) indicate G/U base pairs. Red highlighted hashtags (#) indicated gaps or mismatches, green highlighted hashtags indicate C:A base pairs. The introduced substitution mutation introduced by use of the gGe gRNA is highlighted in yellow (S>P).
