Table 4.

Editing efficiencies by block level of CR3. Transcripts whose gRNAs covered two blocks (DEs and FGs) were included in both blocks for this calculation

Level	Percentage Complete
	TREU 667	TREU 667 (enriched)	EATRO 164 (SDM 79)	EATRO 164 (SDM 80)
Initiated editing	15.1	81.9	6.8	9.4
A	2.2	68.3	1.9	2.3
B	1.8	56.6	1.2	1.8
C	1.7	54.6	0.9	1.5
D	1.6	52.0	0.6	1.1
E	1.2	39.1	0.6	1.0
F	0.8	22.3	0.2	0.4
G/FG	0.4	8.8	0.2	0.3