Skip to main content
. Author manuscript; available in PMC: 2020 Feb 18.
Published in final edited form as: ACS Chem Biol. 2018 Sep 5;13(9):2375–2386. doi: 10.1021/acschembio.8b00520

Figure 3.

Figure 3.

Expanding the genetic code in Drosophila melanogaster. (A) Diagram of UAA incorporation into proteins in flies via an expression cassette integrated into the genome using P-element insertion. (B) Structures of BocK and PropK. (C) Western blots of lysates from ovary and other body tissue demonstrating tissue-specific incorporation of PropK. The full-length protein, including the HA tag, is only expressed when the amber stop codon is suppressed.60 Adapted with permission from Nat. Chem. Biol. 2012, 8, 748. Copyright 2012 Nature Publishing Group.