Structures of coumarin and BODIPY caged substrates; caging groups are shown in red. (a) Structures include D-π-A type (1-5) and D-π-D (6-7) coumarin caged substrates. The structures include caged benzoic acids (1, 4, 6–7), a caged tamoxifen analogue (2), a caged cyclic RGDfK peptide (3), caged glutamic acid (5a) and caged cAMP (5b). (b) BODIPY caged molecules include 4-methoxyphenol (8a), caged histamine (8b, 9), and caged 2,4-dinitrobenzoic acid (10-11).